5p Minus Syndrome
There are many conditions that affect the growth and basic bodily functions in children, due to inheret genetics. One of these conditions called Cri du Chat Syndrome, or chromosome 5p deletion syndrome, is no exception. This condition is characterized by the cry that affected infants make, which sounds like that of a meowing cat. This symptom gave birth to the condition’s name, being French for “the call of the cat”. This sound is often lost by the age of two, but many other side affects remain for the course of the individual’s life. The cry is a result of a compromised larynx and nervous system.
The cause of Cri du Chat Syndrome is a genetic abnormality. The makeup of chromosome five has a missing leg, which often occurs from a random deletion. As with many conditions, it affects the appearance of facial features, and growth development. Many children with this syndrome will have full cheeks and a round face, a down turned mouth, a flat bridge of the nose, low ears and stubby fingers. These features tend to change over time, and the course of the childhood growth.
Cri du Chat Syndrome also affects primarily females, and occurs in one out of every twenty thousand children. The condition will result in difficulty feeding as a child, hindered growth and a low weight at birth. The motor system will also be affected, along with speech. The behavior of the child will also be affected, with extreme moods such as hyperactivity, aggression, and movements that are repeated. Drooling and constipation will also be present. Abnormalities will also appear in cardiac functions, which can result in necessary surgery. Other symptoms can be treated by therapists, such as speech and motor functions. Genetic testing is available for individuals with a chromosome 5p deletion syndrome child, ask your doctor about counseling.
The earliest signs of this condition is the iconic cry that mimics that of a cat. This occurs in young infants, and along with the other physical characteristics, it can be diagnosed by a doctor. The health conditions caused by this syndrome can be treated by medication or corrected with surgery. Although is condition is rare, genetic testing can help you understand the origins and affects the abnormality has on the genetic code. Cri du Chat Syndrome is detected at birth, and depending on the parent’s genes, the condition can be extreme or it can be mild.
